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They have not been researched thoroughly, but it is very likely that they are much less harmful than actual cigarettes because they do not produce the range of damaging chemicals found in tobacco smoke, although they are not entirely harmless

A 2021 publication by the Campaign for Tobacco-Free Kids , a non-profit organization, stated that about 80% of the world's smokers lived in low and middle income countries, and that if current trends were to continue, about a billion people could die from smoking related diseases in the 21st century

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